ObjectiveSelective cyclooxygenase-2 inhibitors (celecoxib) can minimize the gastrointestinal complications related to non-steroidal anti-inflammatory drug (NSAID) use.NAXOZOL is a new combination formulation designed to provide sequential delivery of a non-enteric-coated, immediate-release esomeprazole strontium tetrahydrate 20 mg mantle followed b
Effects of dietary sorghum and triticale on performance, carcass traits and meat pH in broiler chickens
The study was conducted to evaluate the effects of dietary partial corn replacement by white sorghum (WS) or triticale (T) on growth performance, carcass parameters and pH of meat in broilers.One-day-old unsexed Cobb 500 broilers (n=600) were randomly assigned to 3 groups with 4 replicates per treatment.The broilers were fed with Accessories isocal
Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping.
BackgroundCullin-dependent E3 ubiquitin ligases (CDL) are key regulators of protein destruction that participate in a wide range of cell biological processes.The Roc subunit of CDL contains an evolutionarily conserved RING domain that binds ubiquitin charged E2 and is essential for ubiquitylation.Drosophila melanogaster contains three highly relate
Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration
Cellular growth, function, and protection require proper iron management, and ferritin plays a crucial role as the major iron sequestration and storage protein.Ferritin is a 24 subunit spherical shell protein composed of both light (FTL) and heavy chain (FTH1) subunits, possessing complimentary iron-handling functions and forming three-fold and fou